{"id":246496,"date":"2026-10-02T00:11:14","date_gmt":"2026-10-02T00:11:14","guid":{"rendered":"https:\/\/www.stemcellmedellin.com\/?p=246496"},"modified":"2026-10-02T00:11:14","modified_gmt":"2026-10-02T00:11:14","slug":"types-of-stem-cells","status":"publish","type":"post","link":"https:\/\/www.stemcellmedellin.com\/es\/types-of-stem-cells\/","title":{"rendered":"Tipos de c\u00e9lulas madre: de d\u00f3nde provienen y cu\u00e1les se utilizan en terapia."},"content":{"rendered":"\n<div class=\"scm-takeaway\" style=\"background:#f8f4f1;border-left:4px solid #937c80;border-radius:8px;padding:18px 22px;margin:0 0 28px\"><p style=\"margin:0 0 6px;font-weight:700;color:#937c80;text-transform:uppercase;font-size:13px;letter-spacing:.06em\">Short answer<\/p><p style=\"margin:0\">There are four main types of stem cells: <strong>embryonic<\/strong>, <strong>adult<\/strong> (also called tissue-specific, including mesenchymal and blood-forming cells), <strong>perinatal<\/strong> (from the umbilical cord and placenta) and <strong>induced pluripotent stem cells<\/strong> made in the lab. They come from embryos, bone marrow, fat, umbilical cord tissue and blood, or reprogrammed adult cells. Regenerative treatments for joint pain use <strong>mesenchymal (adult or perinatal) cells<\/strong>, not embryonic cells.<\/p><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">What makes a cell a stem cell?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A stem cell can do two things other cells cannot: copy itself many times, and give rise to more specialized cells. How many cell types it can become is called its <strong>potency<\/strong>.<\/p>\n\n\n\n<div style=\"overflow-x:auto;margin:0 0 24px\"><table style=\"width:100%;border-collapse:collapse;font-size:15px\"><thead><tr><th style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;background:#f8f4f1;vertical-align:top\">Potency<\/th><th style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;background:#f8f4f1;vertical-align:top\">Can become<\/th><th style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;background:#f8f4f1;vertical-align:top\">Example<\/th><\/tr><\/thead><tbody><tr><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Totipotent<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Every cell of the body plus the placenta<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">The fertilized egg in its first divisions<\/td><\/tr><tr><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Pluripotent<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Almost any cell of the body<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Embryonic stem cells, induced pluripotent stem cells<\/td><\/tr><tr><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Multipotent<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Several cell types within a family<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Mesenchymal cells (bone, cartilage, fat); blood-forming cells<\/td><\/tr><tr><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Unipotent<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">A single cell type<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Muscle satellite cells, some skin cells<\/td><\/tr><\/tbody><\/table><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Multipotent cells<\/strong> are the ones most relevant to treatment today. They are more limited than pluripotent cells, which also makes them more predictable and safer to use.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The main types of stem cells<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1. Embryonic stem cells<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">They are obtained from the inner cell mass of a blastocyst, an embryo of about five days, usually donated from in vitro fertilization with the consent of the donors. They are pluripotent, which makes them powerful for research but also carries a risk of forming tumors, and their use raises ethical debates. Their use in patients is limited to clinical trials.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">2. Adult (tissue-specific) stem cells<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">They live in many tissues and help maintain and repair them. Two groups matter most in medicine:<\/p>\n\n\n\n<ul style=\"list-style:disc outside;padding-left:1.3em\"><li><strong>Hematopoietic (blood-forming) stem cells<\/strong>, from bone marrow, blood and cord blood. Their transplant is an established treatment for leukemia, lymphoma and other blood disorders.<\/li><li><strong>Mesenchymal stem (stromal) cells<\/strong>, found in bone marrow, fat and other tissues. They can form bone, cartilage and fat, and they release signals that modulate inflammation. The International Society for Cellular Therapy defined the minimum criteria to identify them in 2006.<\/li><\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">3. Perinatal stem cells (umbilical cord and placenta)<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Cord blood is rich in blood-forming stem cells and is the source of most FDA-approved stem cell products. The cord tissue itself, including Wharton&#8217;s jelly, contains mesenchymal cells that are collected after a healthy birth, with the mother&#8217;s consent, without harming mother or baby.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">4. Induced pluripotent stem cells (iPSCs)<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">In 2006 Shinya Yamanaka&#8217;s team showed that adult cells can be reprogrammed into a pluripotent state, a discovery later recognized with the Nobel Prize. iPSCs avoid the use of embryos and are a major research tool, but treatments based on them are still in early clinical trials.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Where do stem cells come from?<\/h2>\n\n\n\n<div style=\"overflow-x:auto;margin:0 0 24px\"><table style=\"width:100%;border-collapse:collapse;font-size:15px\"><thead><tr><th style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;background:#f8f4f1;vertical-align:top\">Source<\/th><th style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;background:#f8f4f1;vertical-align:top\">Main cell type<\/th><th style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;background:#f8f4f1;vertical-align:top\">How it is obtained<\/th><\/tr><\/thead><tbody><tr><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Bone marrow<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Blood-forming and mesenchymal<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Aspiration from the hip bone under local anesthesia<\/td><\/tr><tr><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Fat (adipose tissue)<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Mesenchymal<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Small liposuction<\/td><\/tr><tr><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Umbilical cord blood<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Blood-forming<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Collected from the cord after birth<\/td><\/tr><tr><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Umbilical cord tissue<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Mesenchymal<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Processed from donated cord tissue after birth<\/td><\/tr><tr><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Embryos<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Embryonic (pluripotent)<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Donated IVF embryos, research use<\/td><\/tr><tr><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Reprogrammed skin or blood cells<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Induced pluripotent<\/td><td style=\"border:1px solid #e3dcd8;padding:10px 12px;text-align:left;vertical-align:top\">Laboratory reprogramming<\/td><\/tr><\/tbody><\/table><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Cells from your own body are called <strong>autologous<\/strong>; cells from a donor are <strong>allogeneic<\/strong>. Each has pros and cons: your own cells carry no risk of rejection but require a harvest procedure, and their quality can decline with age; donor cells avoid the harvest but must come from a properly screened and certified source.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Which stem cells are used in therapy today?<\/h2>\n\n\n\n<ul style=\"list-style:disc outside;padding-left:1.3em\"><li><strong>Established:<\/strong> blood-forming stem cell transplants for blood cancers and some immune disorders.<\/li><li><strong>Used, with evolving evidence:<\/strong> mesenchymal stem cells for osteoarthritis, tendon and ligament injuries. See the evidence in our <a href=\"\/stem-cell-therapy-pros-and-cons\/\">pros and cons guide<\/a>.<\/li><li><strong>Research and clinical trials:<\/strong> embryonic and induced pluripotent stem cells, for example in eye diseases, Parkinson&#8217;s disease and diabetes.<\/li><\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">At Stem Cell Medellin, regenerative protocols for <a href=\"\/knee-pain-therapy-medellin\/\">knee<\/a>, <a href=\"\/hip-pain-therapy-medellin\/\">hip<\/a>, <a href=\"\/shoulder-pain-therapy-medellin\/\">shoulder<\/a> and <a href=\"\/back-pain-therapy-medellin\/\">back<\/a> pain work with mesenchymal stem cells. Dr. Catalina Henao explains in your consultation which source is proposed for your case and why.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Frequently asked questions<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">What are the 4 types of stem cells?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Embryonic stem cells, adult or tissue-specific stem cells (including mesenchymal and blood-forming cells), perinatal stem cells from the umbilical cord and placenta, and induced pluripotent stem cells created in the lab.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Where do stem cells come from?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">From embryos, bone marrow, fat tissue, umbilical cord blood and tissue, and from adult cells reprogrammed in the laboratory. Every adult also has stem cells in several tissues.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What is a multipotent stem cell?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A stem cell that can become several cell types within one family. Mesenchymal stem cells, for example, can form bone, cartilage and fat; blood-forming stem cells produce all blood cells.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Are embryonic stem cells used to treat joint pain?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">No. Treatments for joint and tendon pain use adult or perinatal mesenchymal cells. Embryonic stem cells are only used in research and clinical trials.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Which stem cells are FDA approved?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The FDA-approved stem cell products are mostly umbilical cord blood products used for blood and immune disorders. No stem cell product is approved for orthopedic conditions.<\/p>\n\n\n\n<div class=\"scm-refs\" style=\"border-top:1px solid #e3dcd8;margin-top:32px;padding-top:18px;font-size:15px\"><h2 style=\"font-size:22px\">References<\/h2><ol style=\"list-style:decimal outside;padding-left:1.3em\"><li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11463971\/\" target=\"_blank\" rel=\"noopener\">Classes of stem cells: from biology to engineering (2023)<\/a><\/li><li><a href=\"https:\/\/www.aboutstemcells.org\/info\/stem-cell-types\" target=\"_blank\" rel=\"noopener\">About Stem Cells: Types of stem cells<\/a><\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16923606\/\" target=\"_blank\" rel=\"noopener\">Dominici M et al. Minimal criteria for defining multipotent mesenchymal stromal cells. ISCT position statement. Cytotherapy (2006)<\/a><\/li><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16904174\/\" target=\"_blank\" rel=\"noopener\">Takahashi K, Yamanaka S. Induction of pluripotent stem cells from adult fibroblast cultures by defined factors. Cell (2006)<\/a><\/li><li><a href=\"https:\/\/www.fda.gov\/vaccines-blood-biologics\/cellular-gene-therapy-products\/approved-cellular-and-gene-therapy-products\" target=\"_blank\" rel=\"noopener\">FDA: Approved cellular and gene therapy products<\/a><\/li><li><a href=\"https:\/\/www.isscr.org\/treatment-guide\" target=\"_blank\" rel=\"noopener\">ISSCR: A patient&#8217;s guide to stem cell treatments<\/a><\/li><\/ol><p style=\"margin-top:16px\"><strong>Related reading:<\/strong> <a href=\"\/stem-cell-therapy-pros-and-cons\/\">Stem Cell Therapy Pros and Cons<\/a> \u00b7 <a href=\"\/how-stem-cell-therapy-is-administered-in-clinical-settings\/\">How Stem Cell Therapy Is Administered<\/a> \u00b7 <a href=\"\/stem-cell-therapy-protocols\/\">Our Stem Cell Therapy Protocols<\/a><\/p><p style=\"font-size:14px;color:#6b6b6b\">Medically reviewed by <a href=\"\/dr-catalina-henao\/\">Dr. Catalina Henao, MD<\/a>. Last reviewed October 2026. This article is for general information and does not replace a medical consultation.<\/p><\/div>\n\n\n\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"MedicalWebPage\",\"@id\":\"https:\/\/www.stemcellmedellin.com\/types-of-stem-cells\/#medicalwebpage\",\"url\":\"https:\/\/www.stemcellmedellin.com\/types-of-stem-cells\/\",\"name\":\"Types of Stem Cells: Where They Come From and Which Are Used in Therapy\",\"description\":\"Embryonic, adult, mesenchymal, iPS and umbilical cord stem cells explained: what each can do, where they come from and which are used in therapy.\",\"inLanguage\":\"en-US\",\"isPartOf\":{\"@id\":\"https:\/\/www.stemcellmedellin.com\/#website\"},\"about\":{\"@type\":\"Thing\",\"name\":\"Stem cells\"},\"medicalAudience\":{\"@type\":\"MedicalAudience\",\"audienceType\":\"Patient\"},\"lastReviewed\":\"2026-10-01\",\"reviewedBy\":{\"@id\":\"https:\/\/www.stemcellmedellin.com\/#physician\"},\"author\":{\"@id\":\"https:\/\/www.stemcellmedellin.com\/#physician\"},\"publisher\":{\"@id\":\"https:\/\/www.stemcellmedellin.com\/#clinic\"},\"citation\":[{\"@type\":\"CreativeWork\",\"name\":\"Classes of stem cells: from biology to engineering (2023)\",\"url\":\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11463971\/\"},{\"@type\":\"CreativeWork\",\"name\":\"About Stem Cells: Types of stem cells\",\"url\":\"https:\/\/www.aboutstemcells.org\/info\/stem-cell-types\"},{\"@type\":\"CreativeWork\",\"name\":\"Dominici M et al. 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No stem cell product is approved for orthopedic conditions.\"}}]}]}<\/script>\n","protected":false},"excerpt":{"rendered":"<p>Explicaci\u00f3n de las c\u00e9lulas madre embrionarias, adultas, mesenquimales, iPS y del cord\u00f3n umbilical: qu\u00e9 puede hacer cada una, de d\u00f3nde provienen y cu\u00e1les se utilizan en terapia.<\/p>","protected":false},"author":8,"featured_media":244001,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[24],"tags":[],"dipi_cpt_category":[],"class_list":["post-246496","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-stem-cell-therapy"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Types of Stem Cells and Where They Come From<\/title>\n<meta name=\"description\" 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